Amoxicillin Sodium and Clavulanate Potassium for Injection
The indication is 1. Upper respiratory tract infection: sinusitis, tonsillitis, pharyngitis. 2. Lower respiratory tract infection: acute bronchitis, acute attack of chronic bronchitis, pneumonia, pulmonary abscess and bronchiectasis complicated with infection. 3. Urinary system infection: cystitis, urethritis, pyelonephritis, prostatitis, pelvic inflammatory disease, Neisseria gonorrhoeae urinary tract infection. 4. Skin and soft tissue infection: furuncle, abscess, cellulitis, wound infection, abdominal sepsis, etc. 5. Other infections: otitis media, osteomyelitis, sepsis, peritonitis and postoperative infection.
Bacterial resistance is mainly due to the β - lactamases produced by bacteria, which destroy antibiotics before they act on pathogens. Clavulanic acid in this product can block the action of β - lactamase, so as to prevent the emergence of bacterial resistance, and make the bacteria more sensitive to amoxicillin and be quickly killed. Although clavulanic acid itself has almost no antibacterial effect, it can become a broad-spectrum antibiotic with extensive clinical value after being compounded with amoxicillin. This product is effective against the following bacteria:
Gram positive bacteria:
Aerobic bacteria: anthrax *, Corynebacterium, Enterococcus faecalis *, Listeria monocytogenes, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus viridis, Streptococcus agalactiae, Staphylococcus aureus *, coagulase negative Staphylococcus * (including Staphylococcus epidermidis).
Anaerobic bacteria: Clostridium, Enterococcus and Streptococcus.
Gram negative bacteria:
Aerobic bacteria: pertussis, Brucella, Escherichia coli *, Gardnerella vaginalis Haemophilus influenzae *, Helicobacter pylori, Klebsiella *, Legionella, Moraxella catarrhalis * (Bacillus catarrhalis), Neisseria meningitidis *, Pasteurella haemorrhagic, Proteus mirabilis *, Proteus vulgaris *, Salmonella *, Shigella *, Vibrio cholerae, Yersinia enterocolitica *.
Anaerobes: Bacteroides * (including Bacteroides fragilis) and Fusobacterium *.
Because some strains of this genus can produce β - lactamase, they are not sensitive to amoxicillin alone.
This product contains amoxicillin and clavulanic acid, so it is effective to treat the infection caused by amoxicillin sensitive bacteria; the infection caused by amoxicillin sensitive bacteria and β - lactamase producing bacteria is also effective.
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