| Application: | Internal Medicine |
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| Usage Mode: | For external use |
| Suitable for: | Elderly, Children, Adult |
| State: | Solid |
| Shape: | Oral Liquid |
| Type: | Organic Chemicals |
| Samples: |
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| Customization: |
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Audited Supplier | Product name | Streptomycin Sulfate for Inj. |
| Specificaton | 0.75g/1g/5g |
| Certification | GMP ISO9001 ISO14001 |
| Standard | BP |
| fuction | Streptomycin sulfate for injection, the indication is 1. This product is mainly used in combination with other anti-tuberculosis drugs in initial cases of tuberculosis caused by Mycobacterium tuberculosis, or other sensitive Mycobacterium infections. 2. This product can be used solely for the treatment of tularemia, or combined with other antibacterial drugs for the treatment of plague, granuloma inguinal, brucellosis, rodent bite fever, etc. 3. It can also be combined with penicillin or ampicillin to treat endocarditis caused by Streptococcus viridans or Enterococcus. |
| taboo | Patients who are allergic to streptomycin or other aminoglycosides are contraindicated |
| Announcements | 1. Cross allergy Patients who are allergic to one aminoglycoside may also be allergic to other aminoglycosides. 2. Streptomycin should be used with caution in the following situations: (1) Dehydration can increase the blood concentration, which is prone to toxic reactions. (2) No. 8 damages the brain nerves, because this product can cause vestibular nerve and auditory nerve damage. (3) Myasthenia gravis or Parkinson's disease, because this product can cause neuromuscular blockade, resulting in skeletal muscle weakness. (4) Impairment of renal function, because this product has nephrotoxicity. 3. During the course of treatment, pay attention to the following checks regularly: (1) Urine routine and renal function tests to prevent severe nephrotoxicity. (2) Hearing test or audiogram (especially high-frequency hearing) measurement is especially important for elderly patients. 4. Blood drug concentration should be monitored when possible, and the dosage should be adjusted accordingly, especially for neonates, elderly and patients with impaired renal function. If 7.5 mg/kg is administered every 12 hours, the peak plasma concentration should be maintained at 15-30 μg/ml, and the trough concentration should be 5-10 μg/ml; if 15 mg/kg is administered once a day, the peak plasma concentration 56~64μg/ml, trough concentration <1μg/ml. 5. Interference with diagnosis: This product can increase the measured values of alanine aminotransferase (ALT), aspartate aminotransferase (AST), serum bilirubin concentration and lactate dehydrogenase concentration; blood calcium and magnesium The measured value of potassium, sodium concentration may decrease. |
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