Piperacillin Sodium for Injection
Piperacillin sodium for injection is suitable for septicemia caused by sensitive Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter, upper urinary tract and complex urinary tract infections, respiratory tract infections, biliary tract infections, abdominal infections, pelvic infections, skin and soft tissue infections. The combination of piperacillin and aminoglycosides can also be used for the infection of immune deficiency patients with granulocytopenia.
Piperacillin is a semi synthetic penicillin antibiotic with broad-spectrum antibacterial activity. Piperacillin has good antibacterial activity against Escherichia coli, proteus, Serratia, Klebsiella, enterobacter, Citrobacter, Salmonella and Shigella, as well as other gram-negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, Haemophilus influenzae and Neisseria. The product also has certain antibacterial activity against Enterococcus, group A and group B Streptococcus haemolyticus, Streptococcus pneumoniae and Staphylococcus without penicillinase production. Many anaerobes, including Bacteroides fragilis and Clostridium, are also sensitive to piperacillin.
The mechanism of piperacillin is to inhibit the synthesis of bacterial cell wall.
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