Metformin Hydrochloride Tablet
For patients with type II diabetes who are not satisfied with simple diet control, especially those with obesity and hyperinsulinemia, it can not only reduce blood glucose, but also reduce body weight and hyperinsulinemia. For some patients with poor efficacy of sulfonylureas, such as sulfonylureas, small intestinal glycosidase inhibitors or thiazolidinedione hypoglycemic agents, the effect is better than single use. It can also be used in patients with insulin therapy to reduce insulin dosage.
This product is a hypoglycemic drug. This product can reduce fasting and postprandial hyperglycemia in patients with type II diabetes, and HbAlc can be reduced by 1% - 2%. The hypoglycemic mechanism of this product may be as follows:
1. Increase the sensitivity of surrounding tissues to insulin and increase insulin mediated glucose utilization.
2. Increase glucose utilization in non insulin dependent tissues, such as brain, blood cells, kidney, intestine, skin, etc.
3. Inhibit the heterogenesis of liver glycogen and reduce the output of liver sugar.
4 inhibited glucose uptake by intestinal parietal cells,
5. Inhibit the biosynthesis and storage of cholesterol, reduce the level of triglyceride and total cholesterol. Different from insulin, this product has no effect on promoting fat synthesis and lowering blood sugar in normal people. It does not cause hypoglycemia when used alone for type II diabetes.
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