Cefazolin Sodium for Injection
Cefazolin sodium for injection is suitable for the treatment of otitis media, bronchitis, pneumonia and other respiratory tract infections, urinary tract infections, skin and soft tissue infections, bone and joint infections, sepsis, infective endocarditis, hepatobiliary system infections and eye, ear, nose and throat infections caused by sensitive bacteria. This product can also be used as a preventive drug before surgery. This product is not suitable for central nervous system infection. For chronic urinary tract infection, especially with abnormal anatomy of urinary tract, the curative effect is poor. This product is not suitable for the treatment of gonorrhea and syphilis.
Cefazolin is the first generation cephalosporin with broad antibacterial spectrum. Except Enterococcus and methicillin-resistant Staphylococcus, this product has good antibacterial activity against other gram-positive cocci. Streptococcus pneumoniae and Streptococcus haemolyticus are highly sensitive to this product. Diphtheria, anthrax, Listeria and Clostridium are also sensitive to this product. The product has good antibacterial activity against some Escherichia coli, Proteus mirabilis and Klebsiella pneumoniae, but the antibacterial effect on Staphylococcus aureus is poor. Salmonella, Shigella and Neisseria were sensitive to the drug, while other Enterobacteriaceae, Acinetobacter and Pseudomonas aeruginosa were resistant. Neisseria gonorrhoeae was resistant to this drug; Haemophilus influenzae was only moderately sensitive. Gram positive anaerobes and some gram negative anaerobes are sensitive to this product. Bacteroides fragilis was resistant.
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